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Pediatric Surgery

Propofol offered quicker sedation but linked to higher rate of side effects

Published in Clinical Oncology Week, November 28th, 2005

Propofol offered quicker sedation in pediatric cancer but was associated with a higher rate of side effects than midazolam/ketamine.

"Different pharmacologic agents have been used for sedation in children undergoing invasive procedures. The authors prospectively compared the efficacy, the occurrence of adverse effects, cardiovascular parameters, oxygen saturation and induction, and recovery time in propofol with or without morphine versus midazolam/ketamine sedation for procedural sedation in children with malignancies and hematologic disorders," scientists in Germany reported.

"Fifty children received either propofol with or without morphine or...

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