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Lung Cancer

Paclitaxel/carboplatin/etoposide compared to paclitaxel/topotecan

Published in Clinical Oncology Week, January 9th, 2006

The paclitaxel/carboplatin/etoposide chemotherapy regimen was compared to paclitaxel/topotecan regimen in extensive-stage small cell lung cancer.

Researchers in the United States conducted a study "to compare the combination of paclitaxel (Taxol) and topotecan (Hycamtin) with paclitaxel, carboplatin (Paraplatin; Bristol-Myers Squibb), and etoposide (Etopophos, VePesid) in patients with previously untreated extensive-stage small cell lung cancer."

"In this phase II trial, 120 patients were randomly allocated to receive either topotecan (1.5 mg/m2 i.v. days 1, 2, and 3) and paclitaxel (175 mg/m2 i.v.day 1) every 21 days or...

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