Clinical Oncology Week

Breast Cancer - Outcome after preoperative chemotherapy for breast cancer predicted by nomogram

Esophageal Cancer - Esophagectomy is the principle therapeutic option for squamous cell esophageal cancer

Hemangiopericytomas - Precision radiotherapy used in hemangiopericytomas of the central nervous system

Hodgkin Disease - Combined-modality therapy resulted in local control of Hodgkin Disease

Acute Myeloid Leukemia - PAF-R presence on surface of leukemic cells not detected by flow cytometry

Adenocarcinomas - COX-2 is expressed in stromal myofibroblasts surrounding colon adenocarcinomas

Anal Canal Cancer - Tumor response after initial irradiation predicts survival of anal canal cancer

Anal Canal Cancer - Utility of FDG-PET for staging and evaluating cancer of the anal canal assessed

Antioxidants - Manganese superoxide dismutase modifies the expression of angiogenic growth factors

Antiviral Therapy - Gemcitabine enhances ganciclovir-mediated bystander cytotoxicity

Apoptosis - Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis

Apoptosis - Data advance knowledge in apoptosis research

Apoptosis - HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis

Awards - U.S. NIH NIAID awards 2-year grant for development of influenza A virus vaccine

Biomedical Engineering - A new molecular conjugate vector improves tumor targeting, imaging, and therapy

Bladder Cancer - Abating heat shock protein 70 caused enhanced sensitivity to mitomycin C in bladder cancer

Bladder Cancer - Assay is more effective than conventional test for recurrent disease

Bladder Cancer - Relation between NAT2 slow acetylation and bladder cancer examined

Bone Marrow Metastases - Tc-99m-MIBI used to detect bone marrow metastases in childhood solid tumors

Brain Cancer - Transnasal endoscopic resection effective for clival tumors

Breast Cancer - Adiposity is associated with both premenopausal and postmenopausal breast cancer risk

Breast Cancer - Age previously excluded elderly patients with breast cancer from local treatment

Breast Cancer - CMF compared to CAF with and without tamoxifen in node-negative breast cancer

Breast Cancer - Category of complex breast cysts helped determine course of clinical management

Breast Cancer - Docetaxel proves more effective than paclitaxel in women with node-positive breast cancer

Breast Cancer - Epirubicin/paclitaxel compared with epirubicin/cyclophosphamide in breast cancer

Breast Cancer - Epstein-Barr virus found in cancer tissue may impact efficacy of treatment

Breast Cancer - Melatonin enhanced inhibitory effect of aminoglutethimide in breast cancer cells

Breast Cancer - Molecular interaction found to trigger particularly aggressive form of disease

Breast Cancer - Nuclear medicine imaging helps predict patients' response to hormonal therapy

Breast Cancer - Older age linked to lower risk of lymph node metastasis in breast cancer

Breast Cancer - Oncoprotein sp185(HER-2) has poor diagnostic performance for malignant effusions

Breast Cancer - Polymorphisms of DNA mismatch repair gene hMSH2 linked to breast cancer risk

Breast Cancer - Protein fragment may help predict breast cancer outcome

Breast Cancer - PrxII expression related to radiation-resistant MCF-7 breast cancer cells

Breast Cancer - RBC count up, alkaline phosphatase level down in patients receiving both CMF and tamoxifen

Breast Cancer - Reports advance knowledge in breast cancer research

Breast Cancer - Researchers publish new studies and findings in the area of breast cancer

Breast Cancer - Role of imaging in evaluating metastatic disease from breast cancer reviewed

Breast Cancer - Sex hormones not useful predictors of breast cancer risk

Breast Cancer - Stress-management intervention reduced depression among breast cancer patients

Breast Cancer - Studies advance knowledge in breast cancer research

Breast Cancer - Tc-99m dextran 500 deemed better than Tc-99m phytate in detecting breast cancer

Breast Cancer - Use of efaproxiral in brain metastases from breast cancer improved survival

Breast Cancer Screening - Community/church-based education may increase mammography rates for African-American women

Breast Cancer Screening - Differences are seen in specificity and sensitivity of diagnostic mammography in Black women

Breast Cancer Screening - Illustration of breast cancer risk can help women make better decisions about mammography

Breast Cancer Screening - Recursive partitioning may help design programs to promote regular mammograms

Breast Cancer Therapy - Bi-weekly fluorouracil/epirubicin/cyclophosphamide regimen has long-term safety profile

Breast Cancer Therapy - Small benefits of endocrine therapy persuade some women to choose treatment

Cancer Coping - Quality of communication between parents and children in discussing parental cancer reviewed

Cancer Diagnosis - Predictors of posttraumatic stress disorder following cancer identified

Cancer Gene Therapy - Adenoviral vectors targeting angiogenesis enhance prostate tumor suppression

Cancer Gene Therapy - Antisense Bcl-2 sensitizes prostate cancer cells to radiation

Cancer Gene Therapy - Combination nonviral gene therapy and radiotherapy is effective for squamous cell carcinoma

Cancer Gene Therapy - Endothelial cell transplantation permits gene therapy in experimental gliomas

Cancer Gene Therapy - Nonviral jet-injection gene transfer is an effective therapy for colon carcinoma

Cancer Gene Therapy - Retargeted gene therapy blankets malignant glioma without triggering angiogenesis

Cancer Prevention - Green tea polyphenols avert ultraviolet radiation-induced skin cancer

Cancer Research - Biotech company submits new drug application to U.S. FDA for monoclonal antibody

Cancer Risk Factors - Body mass index positively affects cancer risk factors for certain cancers

Cancer Risk Factors - Higher serum levels of estrone in postmenopausal women are associated with high fat intake

Cancer Therapy - Bioactive cyclic peroxides isolated from marine sponge Plakortis zyggompha

Cancer Therapy - COX-2 inhibitor augments the anticancer properties of docetaxel in lung tumors

Cancer Therapy - Constitutively active Notch-1 increases synthesis of the PTEN tumor suppressor

Cancer Therapy - Findings describe new data in cancer therapy research

Cancer Therapy - L-asparaginase may indicate chemotherapy dose changes for obese children with ALL

Cancer Therapy - New findings in the area of cancer therapy detailed

Cancer Therapy - No increased efficacy seen in trial of low-dose total body irradiation for melanoma

Cancer Therapy - Novel extracellular vesicles mediated anticancer drug resistance

Cancer Therapy - Novel flavonoid derivatives evaluated for anticancer activity

Cancer Therapy - Novel thermosensitive 5-fluorouracil-cyclotriphosphazene conjugates evaluated

Cancer Therapy - Oncolytic adenovirus expressing a p53 variant replicates in cervical cancer

Cancer Therapy - Pediatric malignant peripheral nerve sheath tumor treated by surgical resection

Cancer Therapy - Pegfilgrastim administered to prevent neutropenia in pediatric cancer patients

Cancer Therapy - Phase I/II trial of treatment for non-small cell lung cancer initiated

Cancer Therapy - Phase II studies with Panzem NCD begin

Cancer Therapy - Piperazinobenzopyranones and phenalkylaminobenzopyranones inhibited ABCG2

Cancer Therapy - Research add new data to cancer therapy body of knowledge

Cancer Therapy - Sequential 5-fluorouracil and cisplatin may benefit patients with metastatic colorectal cancer

Cancer Therapy - Smad7 expression may repress metastasis of mouse mammary carcinoma cells

Cancer Therapy - Study conduct efficiency of pediatric phase I oncology trials investigated

Cancer Therapy - Study shows combination treatment for ovarian cancer significantly improves survival

Cancer Therapy - WX-G250 plus LD-IL-2 provides better outcome in renal cell carcinoma patients

Carcinoma Ex Pleomorphic Adenoma - Low maspin expression associated with carcinoma ex pleomorphic adenoma

Cervical Cancer - Deutsche BKK to implement routine HPV testing for cervical cancer screening in Europe

Cervical Cancer - Fluorouracil plus radiotherapy did not improve cervix cancer over cisplatin

Cervical Cancer - HIV infection associated with increased risk of cervical cancer precursor

Cervical Cancer - Intra-arterial chemotherapy with and without embolization compared in cervical cancer

Cervical Cancer - Prevalence of cervical cancer in Indian women suggests urgent need for screening programs

Cervical Cancer - Recent findings illuminate research in cervical cancer

Cervical Cancer - Researchers provide details of new studies and findings in the area of cervical cancer

Cervical Cancer - Researchers publish new studies and findings in the area of cervical cancer

Cervical Cancer - Researchers report details of new studies and findings in the area of cervical cancer

Cervical Metastasis - S100A2 expression used to predict late cervical metastasis in OSCC

Chemotherapy - U.S. FDA approves EMEND for the prevention of nausea and vomiting associated with chemotherapy

Clinical Trials - Patient enrollment initiated in phase 3 clinical trial for oral cancer detection drug

Clinical Trials - Phase 1 trial initiated on heat shock protein 90 inhibitor for treating GI stromal tumors

Clinical Trials - Phase 3 multiple myeloma trial with thalidomide reaches prespecified interim endpoint

Clinical Trials - Positive results from trial of oral spray for bioequivalent to Zofran reported

Clinical Trials - Second phase 1 clinical trial for third generation cancer drug taxane initiated

Collaborations - Collaboration expanded to develop molecular diagnostic test for early detection of lung cancer

Collaborations - Collaboration to study effect of drug combination in metastatic breast cancer

Collaborations - Umbrella scientific agreements signed for aerodigestive disease studies

Colon Cancer - An oxaliplatin regimen is efficacious in advanced stage colorectal cancer

Colon Cancer - Chromosome arms that correlate with colon cancer metastases identified

Colon Cancer - Microarray-based prognosis predictor may be feasible

Colon Cancer - Pleural effusion following hepatic radiofrequency used to treat hepatic tumors

Colon Cancer - Raltitrexed-oxaliplatin compared to raltitrexed-irinotecan in colorectal cancer

Colon Cancer - Strategy for diagnosis of hereditary nonpolyposis colorectal cancer devised

Colorectal Cancer - Genetic polymorphisms and alcohol linked to colorectal cancer in Japan

Colorectal Cancer - Genomic fragments methylated specifically in colorectal carcinoma screened

Colorectal Cancer - Rectal cancer patient treatment compared between low- and high-volume surgeons

Cryptosporidiosis - Incidence of cryptosporidiosis among Filipino cancer patients studied

DNA Repair - Protein amplifies DNA injury signals

DNA Research - Impaired DNA replication within progenitor cell pools promotes leukemogenesis

DNA Research - Novel INHAT repressor modulates the transcriptional activity of p53

Developmental Biology - Retinoblastoma and RNA interference-related genes negatively regulate nuclear divisions

Diagnostic Imaging - A new trimodal marker may enhance tumor localization before breast surgery

Diagnostics - Noninvasive genetic screening test detects oral preneoplastic lesions

Diagnostics - Radiolabeled annexin A5 may be developed as a cell-death monitor

Diagnostics - Study indicates improved DNA marker formulation has over 80% sensitivity for detecting colon cancer

Disease Associations - Necrobiotic palisading granulomas can be associated with breast carcinoma

Disease Associations - Withdrawal of bisphosphonates not recommended for necrosis of the jaws

Drug Development - A ginseng saponin metabolite may fight cancer by blocking matrix metalloproteinase

Drug Development - AVN944 phase I trial initiated in cancer patients

Drug Development - Findings describe new data in drug development research

Drug Development - Nitric oxide-donating aspirin induced apoptosis in human colon cancer cells

Drug Development - Novel embelin derivatives show anticancer and antimitotic activity

Drug Development - Onconase phase III trial enrolls more than 300 patients

Drug Development - Phase I trial initiated for targeted anticancer drug ARRY-334543

Drug Development - Researchers' findings advance drug development research

Drug Research - Anti-endoglin antibody blocks angiogenesis and achieves expected pharmacokinetics in monkeys

Drug Resistance - Docetaxel and cisplatin use separate pathways to challenge cancer growth

Ductal Carcinoma In Situ - Separate cavity margin sampling during breast lumpectomy reduced need for reexcisions

Ear Cancer - Radical radiotherapy alone used to treat glomus jugulare and tympanicum tumors

Environmental Health - Cancer mortality of UK electricity generation and transmission workers studied

Ependymoma - Radiation dosimetry predicted IQ after CRT in pediatric patients with ependymoma

Esophageal Cancer - Chemoradiosensitivity of esophageal cancer predicted by serum protein profiling

Esophageal Cancer - Salvage radiation therapy used to treat residual superficial esophageal cancer

Ewing Tumors - Radiotherapy used to treat Ewing tumors of the vertebrae

Finance - Biopharma company completes sale of 4,025,000 shares of common stock

Finance - Imaging-radiation therapy system developer raises $14 million in private financing round

Finance - Nanobiotechnology company receives $750,000 investment

Finance - Radiation therapy products company reports revenues of $6.9 million for fourth quarter

Finance - U.S. Tarceva sales increase 15% over the third quarter to $83.9 million

Fitness & Wellness - Low physical activity and high adiposity decreased recovery and survival in patients

Follicular Lymphoma - Reactive germinal centers in follicular lymphoma indicated limited disease stage

Gastric Cancer - Anticancer drugs regulate peptide transporter 1 in gastric cancer cells

Gastric Cancer - Neoadjuvant radiochemotherapy used to treat locally advanced gastric cancer

Gastric Cancer - Polyglycine expansions in eRF3/GSPT1 associated with gastric cancer risk

Gastric Cancer - TP53BP2 locus associated with risk of gastric cancer in Koreans

Gastric Cancer - Vascular endothelial growth factor D predicts the outcomes of patients with gastric carcinoma

Gastric Cancer - ZD6474 inhibits gastric cancer tumor growth and intraperitoneal dissemination

Gastroenteropancreatic Neuroendocrine Tumors - Molecular genetics of gastroenteropancreatic neuroendocrine tumors discussed

Gene Delivery - Ethylene glycol functions in asialoglycoprotein receptor targeted gene delivery

Gene Research - HER3 genomic gain does not denote lung cancer response to gefitinib

Gene Therapy - Adenovirus genome insertion sites utilize splicing machinery for therapeutic gene expression

Genetics & Genomics - Differential coexpression analysis may facilitate cancer research