Mantle Cell Lymphoma
Hypersensitivity to mosquito bites might indicate mantle cell lymphoma
Published in Clinical Oncology Week, February 6th, 2006
According to a study from Japan, "HMB is known to be an allergic reaction and also a skin symptom in some cases of natural killer cell leukemia/lymphoma associated with Epstein-Barr virus (EBV) infection. We describe a patient who had suffered from HMB for 5 years, and subsequently developed MCL, which resembled chronic lymphocytic leukemia in the early phase."
"EBV monoclonality was not detected in lymph nodes by Southern blotting. Serum levels of interleukin-4 and IgE were increased, but they decreased and HMB disappeared when MCL was predominant,"...
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