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Adenomatous Polyposis

Pancreas-sparing duodenectomy found effective in treating familial adenomatous polyposis

Published in Clinical Oncology Week, February 27th, 2006

Pancreas-sparing duodenectomy could be used to treat familial adenomatous polyposis.

"Duodenal adenocarcinoma remains the leading cause of cancer death in familial adenomatous polyposis patients following colectomy. Stratification based on Spigelman's criteria provides a means for determining therapy," scientists in the United States reported.

"Spigelman stage IV patients have been selected for pancreas-sparing duodenectomy. Twenty-one patients underwent resection between 1992 and 2004, with a mean age of 58±11 years. The mean time from colectomy to duodenectomy was 27±13 years. Invasive cancer was found in the distal duodenum in 1...

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