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Cancer Research

Genetics research may hold key to destroying cancer cells

Published in Clinical Oncology Week, February 27th, 2006

Tumor cells are capable of switching on a molecular "force field" to fend off treatments aimed at killing them. Now University of Florida (UF) researchers have found a chink in that armor.

Tumor cells churn out an enzyme that bonds with a protein, creating a protective barrier that deflects damage from radiation or chemotherapy and promotes tumor cell survival. But in laboratory experiments, UF scientists were able to block the union, and the malignant cells died. The findings are opening new avenues of research that could lead to improved cancer therapies, the researchers reported in the journal Cancer Research.

"We have found a gene called...

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