Esophageal Cancer
Chinese esophageal squamous cell carcinoma linked to aberrant RASSF1A gene
Published in Clinical Oncology Week, April 3rd, 2006
According to a study from the People's Republic of China, "3p21 is an important locus harbouring critical TSG, which are implicated in the pathogenesis of multiple tumours, including oesophageal carcinoma. RASSF1A is a 3p21.3 candidate TSG frequently inactivated by promoter methylation in multiple tumours."
"We investigated RASSF1A promoter methylation and gene expression in Chinese ESCC to compare it to data from Japanese patients," explained M.L. Wong and colleagues, University of Hong Kong....
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