Published in Clinical Oncology Week, May 1st, 2006
"The role of the mismatch repair gene PMS2 in HNPCC is not fully clarified. To date, only 7 different heterozygous truncating PMS2 mutations have been reported in HNPCC-suspected families," researchers in the Netherlands reported.
"Our aim was to further assess the role of PMS2 in HNPCC," explained Y.M.C. Hendriks and colleagues, Leiden University. "We performed Southern blot analysis in 112 patients...
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