Published in Clinical Oncology Week, May 1st, 2006
Study 1: According to recent research from People's Republic of China, proteasome subunits and lysosomal proteases are up-regulated in hepatocellular carcinomas (HCCs) of the HBx gene.
"Chronic infection of hepatitis virus B (HBV) has been proven to be one of the most important risk factors of hepatocellular carcinoma (HCC). HBx has been shown to function in the viral life cycle and the development of HCC.
"Recently, we have reported that HBx transgenic mice (p21-HBx), generated by gene knockin, develop HCC at the...
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