Published in Clinical Oncology Week, June 26th, 2006
Study 1: Endogenous pretreatment plasma folate modulated the magnitude of the methotrexate effect in leukemia and Hodgkin lymphoma pediatric patients.
According to researchers in Czech Republic, "To evaluate the influence of pretreatment plasma folate concentrations on methotrexate exposure in children with acute lymphoblastic leukemia/non-Hodgkin lymphoma treated with high-dose methotrexate, we assessed time profiles of plasma homocysteine, folate, and vitamin B, concentrations in children treated with high-dose methotrexate with leucovorin...
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