Published in Clinical Oncology Week, September 4th, 2006
The study found that the enzyme NOX5-S is affected by exposure to acid and that it produces stress on cells, activating genes that lead to DNA damage. For the first time, researchers have outlined the signaling pathway from cells damaged by acid, to the progression of esophageal cancer. They believe the same process may happen in the body when cells are exposed to acid reflux.
"The role of acid is controversial. But we show that by exposing cells to acid for short periods of...
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