Researchers from University of Texas, M.D. Anderson Cancer Center describe findings in prostate cancer

New investigation results, "Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression," are detailed in a study published in Modern Pathology. According to recent research published in the journal Modern Pathology, "Prostate carcinoma is a hormonally driven age-related neoplasm. Cellular senescence is an age-related process where cells remain metabolically active but in a growth-arrested state at the G1 phase. p14(ARF), p15(INK4b), and p16(INK4a), which are known to regulate G1 cell cycle arrest, and the tumor necrosis factor receptor superfamily member decoy receptor 2 (DCR2), have been recently identified as senescence markers."

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