Lung Cancer Prevention
Reports on lung cancer prevention findings from Tufts University, Human Nutrition Research Center on Aging provide new insights
Published in Clinical Oncology Week, January 22nd, 2007
A new study, "9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2," is now available. According to recent research from the United States, "9-cis-Retinoic acid (9cRA) binds both retinoic acid receptors (RARs) and retinoid X receptors (RXRs) and has been shown to be a potential chemopreventive agent both in lung cancer cell culture studies and in clinical trials studying former smokers. However, direct evidence of the efficacy of 9cRA against lung tumor development in vivo is lacking."
"In the present study, we determined whether treatment with 9cRA has the...
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