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Bladder Cancer Cell Biology

New data from University of Texas, Department of Urology illuminate research in bladder cancer cell biology

Published in Clinical Oncology Week, February 19th, 2007

A report, "Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy," is newly published data in Lancet Oncology. "Deregulation of apoptosis is a characteristic of human carcinogenesis. We aimed to investigate expression of the apoptosis markers Bcl-2, caspase-3, P53, and survivin and the association with oncological outcomes of patients treated by radical cystectomy and bilateral lymphadenectomy for urothelial-cell carcinoma of the bladder," researchers in the United States report.

"Bcl-2, caspase-3, P53, and survivin immunostaining was undertaken on serial tissue microarrays containing cores from 226...

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