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Cancer Gene Therapy

A search for biomarkers for early detection of colorectal cancer

Published in Clinical Oncology Week, October 8th, 2007

Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. The research article describing this work entitled “Differential Expression of Mimecan and Thioredoxin Domain-Containing Protein 5 in Colorectal Adenoma and Cancer: A Proteomic Study” will be featured in Experimental Biology and Medicine.

Adenoma is the major precursor lesion of colorectal cancer, one of the most common cancers worldwide. The elucidation of the molecular mechanism underlying adenoma is essential for early detection, prevention and intervention of colorectal cancer.

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