Hepatocellular Cancer
Researchers from Carnegie Mellon University, Department of Biological Sciences detail findings in hepatocellular cancer
Published in Clinical Oncology Week, October 29th, 2007
A new study, 'Endosomal trafficking and proprotein convertase cleavage of cis golgi protein GP73 produces marker for hepatocellular carcinoma,' is now available. According to a study from the United States, "'Serum GP73 levels are significantly increased in patients with hepatocellular carcinoma (HCC), potentially providing a marker for early detection. However, GP73 is an integral membrane protein localized to the cis Golgi and is not known to be secreted."
"Based on its presence in sera, we sought to determine whether GP73 might normally be released from cells and to elucidate the mechanism of this release. Indeed, a soluble form of GP73 was released from cultured...
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