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Breast Cancer

Studies from R. Torrisi and co-researchers update current data on breast cancer

Published in Clinical Oncology Week, February 11th, 2008

"The prevalence of HER2 amplification according to the percentage of positively stained cells, of polysomy 17 and their correlation with clinical and pathologic characteristics were retrospectively evaluated in a population of 415 breast cancers where fluorescence in situ hybridisation (FISH) was performed to clarify HER2 status previously determined by immunohistochemistry. Forty-two tumours with intense and complete staining in > 50% of cells were selected from the same database as internal controls," scientists writing in the European Journal of Cancer report.

"Among the 415 cases, 233 tumours were IHC 1+, 168 tumours were 2+ and 14 tumours showed an...

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