Published in Clinical Oncology Week, March 10th, 2008
It is well established that steroid receptor coactivator-3 (SRC-3/AIB1) plays key roles in cell growth, reproduction, metabolism and cytokine signaling, is overexpressed in many cancers and is a major player in tumorigenesis and cancer progression. It is also clear that protein kinases are often overactive in cancers and that distinct patterns of phosphorylation,...
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