RNA Research

Neuronal regulators offer potential targets for cancer

Published in Clinical Oncology Week, March 31st, 2008

Boston, Mass. (March 19, 2008) -- Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells. When a breast cell begins making the proteins normally produced in neurons, for example, it can acquire cancerous properties.

Now, researchers in Stephen Elledge's laboratory at Harvard Medical School (HMS) have identified some of the switches that control this transformation, providing promising new therapeutic targets in some types of cancer. Their results appear in the March 20 issue of Nature.

"These switches play an important physiologic role in neural...

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Source: Clinical Oncology Week (2008-03-31)

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