Myeloma

Research from University of Bari, Medical Department yields new findings on myeloma

Published in Clinical Oncology Week, May 5th, 2008

According to a study from Bari, Italy, "Vasculogenesis is a physiologic process typical of fetal,development in which new blood vessels develop from undifferentiated precursors (or angioblasts). In tumors, near angiogenesis, vasculogenesis contributes to the formation of the microvascular plexus that is important for diffusion."

"Here, we show that hematopoietic stem and progenitor cells (HSPC) of multiple myeloma (MM) patients are able to differentiate into cells with endothelial phenotype on exposure to angiogenic cytokines. Circulating HSPCs were purified with an anti-CD133 antibody from patients with newly diagnosed MM before autologous transplantation and exposed...

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Source: Clinical Oncology Week (2008-05-05)

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