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Chemotherapy

Reports from University of Cologne advance knowledge in chemotherapy

Published in Clinical Oncology Week, May 12th, 2008

"Intensive chemotherapy with severe neutropenia is associated with invasive fungal infections (IFIs) leading to high mortality rates. During leukaemia induction chemotherapy, IFI often prohibited further curative treatment, thus predisposing for leukaemia relapse," scientists writing in the Journal of Antimicrobial Chemotherapy report.

"Continuing myelosuppressive chemotherapy after diagnosis of IFI has become feasible with the now expanding arsenal of safe and effective antifungals. Secondary prophylaxis of IFI is widely administered, but reliable data on outcome and risk factors for recurrent IFI during subsequent chemotherapy are not available. This study...

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