Oregon Health & Science University
OHSU Cancer Institute researchers pinpoint how smoking causes cancer
Published in Clinical Oncology Week, May 26th, 2008
The research will be published, May 12, in the British Journal of Cancer.
Researchers discovered that the production of a protein called FANCD2 is slowed when lung cells are exposed to cigarette smoke. Low levels of FANCD2 leads to DNA damage, triggering cancer. Cigarette smoke curbs the production of 'caretaker' proteins, like FANCD2, which normally prevent cancer by fixing damages in DNA and causing faulty cells to commit suicide.
Research has shown that smoking is strongly linked...
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