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Gallbladder Cancer

Data from A. Srivastava and colleagues advance knowledge in gallbladder cancer

Published in Clinical Oncology Week, July 7th, 2008

"Inflammation of gallbladder is an established risk factor for gallbladder cancer (GBC) pathogenesis. Chemokine receptors play crucial role in antitumour immunity and are involved in inflammation and pathogenesis of cancers," investigators in Lucknow, India report.

"Present study was aimed to examine the role of CCR5 Delta 32 polymorphism in conferring genetic susceptibility to GBC. Present case-control study included 144 proven GBC patients and 210 healthy controls. Genotyping was done by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Statistically significant difference was observed in distribution of CCR5+/Delta 32 genotype (P =...

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