Broad Institute of Mit and Harvard

Researchers unveil near-complete protein catalog for mitochondria

Published in Clinical Oncology Week, July 21st, 2008

Imagine trying to figure out how your car's power train works from just a few of its myriad components: It would be nearly impossible. Scientists have long faced a similar challenge in understanding cells' tiny powerhouses — called "mitochondria" — from scant knowledge of their molecular parts.

Now, an international team of researchers has created the most comprehensive "parts list" to date for mitochondria, a compendium that includes nearly 1,100 proteins. By mining this critical resource, the researchers have already gained deep insights into the biological roles and evolutionary histories of several key proteins. In addition, this careful cataloging has identified a...

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Source: Clinical Oncology Week (2008-07-21)

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