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Research

Bacterial peptide provides new insight into common tumor suppressor

Published in Clinical Oncology Week, July 21st, 2008

Scientists have identified a new antitumor drug that might prove useful in developing treatments for a multiple human cancers. The research, published by Cell Press in the July 8 issue of the journal Cancer Cell, advances the understanding of one of the most frequently disrupted tumor suppressor proteins in human cancer and provides new insight into the regulation of the complex process of cellular protein degradation under normal and pathological conditions.

"The cyclin kinase inhibitor p27kip1 is one of the most frequently dysregulated tumor suppressor proteins in human cancers and it correlates directly with patient prognosis," explains study author Dr. Nisar P....

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