Published in Clinical Oncology Week, September 15th, 2008
"Therefore, targeting cancer stem cells may improve patient survival. We interrogated the role of a neuronal cell adhesion molecule, LICAM, in glioma stem cells as LICAM regulates brain development and is expressed in gliomas. LICAM' and CD133' cells cosegregated in gliomas, and levels of LICAM were higher in CD133' glioma cells than normal neural progenitors. Targeting LICAM using...
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