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Colon Cancer

Research reports from D.C. Garciaolmo and co-authors provide new insights into colon cancer

Published in Clinical Oncology Week, October 20th, 2008

"The interactions between a host's normal cells and tumor cells appear to be of significant importance during the development of tumors. In the present study, we examined this issue using a cancer model in vivo in which tumor cells were tagged with a reporter gene for green fluorescent protein (GFP)," investigators in Albacete, Spain report.

"We used a model of colon cancer in immunocompetent rats, which were given a subcutaneous injection of tumor cells that had been transfected with a gene for GFP. We found that the number of fluorescent cells decreased with the progression of the primary tumors and that lymph node and lung metastases were never macroscopically...

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