Cancer Gene Therapy
Studies from University of Heidelberg, Department of Urology in the area of cancer gene therapy published
Published in Clinical Oncology Week, January 12th, 2009
Current study results from the report, 'Evaluation of cytotoxic effects induced by bcl-2 and bcl-xL antisense-oligodeoxynucleotides in normal urothelium and transitional cell carcinoma,' have been published. "We report on cytotoxic effects of bcl-2 and bcl-xL antisense-oligodeoxynucleotides (AS-ODNs) in benign urothelial and transitional cell carcinoma (TCC) cell lines. The benign urothelial cell line (UROtsa) and four TCC cell lines (UM-UC-3, RT 112 , HT 1197 and T 24/83) were incubated with bcl-2 and bcl-xL AS-ODNs and cell mortality rates were assessed," investigators in Mannheim, Germany report.
"Bcl-2 and bcl-xL AS-ODN treatment resulted in low toxicity in UROtsa...
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