Oncology

Data on oncology reported by researchers at Xi'an Jiao Tong University, Department of Medical Oncology

Published in Clinical Oncology Week, January 12th, 2009

Fresh data on oncology are presented in the report 'Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro.' "Mammalian cells grow in three-dimensions (3-D) in vivo. Commonly used two-dimensional (2-D) cell cultures are inadequate to recreate the biological microenvironment of tumor cells," researchers in People's Republic of China report.

"The potentially different outcomes from 2-D and 3-D culture systems may have a significant impact on the relevance of experimental findings. The purpose of this study was to characterize the human hepatoma cell line HepG2 in 2-D and 3-D cultures. HepG2 cells in 2-D and 3-D cultures were treated with...

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Source: Clinical Oncology Week (2009-01-12)

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