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Non-Small Cell Lung Cancer

Research from C.P. Schneider and co-authors provides new data about non-small cell lung cancer

Published in Clinical Oncology Week, February 2nd, 2009

According to a study from Germany, "Relationships between clinical outcomes and epidermal growth factor receptor (EGFR)-related tumor markers were investigated in patients with advanced non-small cell lung cancer. Patients with stage IIIB/IV non-small cell lung cancer (0-2 prior regimens) received erlotinib (150 mg PO per day)."

"Response and survival were evaluated, and tumor samples were assessed by immunohistochemistry (EGFR, phosphorylated mitogen-activated protein kinase, and phosphorylated AKT protein expression), fluorescence in situ hybridization (FISH; EGFR gene copy number), and DNA sequencing (EGFR. KRAS gene imitations). Among, 311 patients, 8% had a...

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