Cancer
Studies from Akita University, Medical Department reveal new findings on cancer
Published in Clinical Oncology Week, March 16th, 2009
According to recent research published in the journal Cancer Science, "Recent progress in cancer biology research has shown that abnormal proliferation in tumor cells can be attributed to aberrations in cell cycle regulation, especially in G(1) phase. During the course of searching for microbial metabolites that affect cell cycle distribution, we have found that simaomicin alpha, a polycyclic xanthone antibiotic, arrests the cell cycle at G(1) phase."
"Treatment of T-cell leukemia Jurkat cells with 3 nM simaomicin alpha induced an increase in the number of cells in G(1) and a decrease in those in G(2)-M phase. Cell cycle aberrations induced by simaomicin alpha...
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