American Association for Cancer Research

Increase in p53 mutation linked to advanced colorectal cancer in blacks

Published in Clinical Oncology Week, April 13th, 2009

Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Understanding the relationship between molecular defects and differences in colorectal cancer incidence, aggressiveness and clinical outcomes is important in individualizing the treatment and in eliminating racial disparities.

"Several studies have identified a disparity between African-Americans and whites for colorectal cancer. What this study does is pinpoint a possible...

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Source: Clinical Oncology Week (2009-04-13)

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