Immunotherapy
Studies from Hokkaido University, Institute for Genetic Medicine update current data on immunotherapy
Published in Clinical Oncology Week, April 13th, 2009
Researchers detail in 'Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells,' new data in immunotherapy. "MAGE-A4 has been considered as an attractive cancer-testis (CT) antigen for tumor immunotherapy. It has been well accepted that T-helper type 1 (Th1) cell-dominant immunity is critical for the successful induction of antitumour immunity in a tumour-bearing host," investigators in Sapporo, Japan report.
"The adoptive Th1 cell therapy has been shown to be an attractive strategy for inducing tumor eradication in mouse systems. However, Th1-cell therapy using human tumour-specific Th1 cells, which were expanded...
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