Published in Clinical Oncology Week, April 27th, 2009
"However, it is well established that a subgroup of patients with stage II are at high risk for recurrence within their lifetime and should be considered for adjuvant chemotherapy. The present work was designed to study the prognostic value of nuclear DNA content in stage H CRC of patients with long-term follow-up. Isolated nuclei from 50 mu m-thick paraffin sections of tissue samples from 253 patients with stage II CRC, who had undergone bowel...
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