Breast Cancer
Research reports on breast cancer from University of Tokyo, Medical Department provide new insights
Published in Clinical Oncology Week, May 25th, 2009
"To investigate the mechanism underlying the nongenomic action of ER alpha in breast cancer cells, we generated a construct of membrane-targeted ER alpha (memER), an expression vector of ER alpha without the nuclear localizing signal and including instead the membrane-targeting sequence of Src kinase. MemER was stably expressed in human breast cancer MCF-7 cells. Cell migration test and tumorigenic assay in nude mice...
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