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Keratosis
Research in the area of keratosis reported from Kyushu University, Department of Dermatology
June 29th, 2009
Researchers detail in 'Stromal CD10 expression, as well as increased dermal macrophages and decreased Langerhans cells, are associated with malignant transformation of keratinocytes,' new data in keratosis. "It has become evident that resident stromal cells, such as fibroblasts and inflammatory cells, are involved in the metastatic process, including proliferation or migration of malignant neoplasms. We analyzed CD10+ stromal cells, dermal macrophages and Langerhans cells (LCs) in skin tumors," scientists in Fukuoka, Japan report. "Immunohistological staining was performed with markers for macrophages (CD68), LC (CD1a), stromal fibroblasts (CD10) and cell proliferation...
Source: Clinical Oncology Week (2009-06-29)
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