Clinical Oncology Week
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Colon Cancer
Scientists at Fourth Military Medical University target colon cancer
August 3rd, 2009
According to recent research published in the journal Biological & Pharmaceutical Bulletin, "NDRG2, a new member of the N-Myc downstream-regulated gene (NDRG) family, is a focus for study at present. Up to now, its expression and function in carcinoma remain to be elucidated." "In this study, using a colorectal cancer tissue array and a series of 213 colorectal cancer samples, the relationship between Ndrg2 and c-MYC expression and tumor differentiation level was investigated. Immunohistochemistry showed that Ndrg2 expression was reduced and that c-Myc was increased in colorectal carcinomas. In addition, Ndrg2 protein levels increased from poorly differentiated...
Source: Clinical Oncology Week (2009-08-03)
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