Cancer
Researchers at National University target cancer
Published in Clinical Oncology Week, October 26th, 2009
"In cancer patients, MUC1 glycoprotein may carry Lewis y which could be involved in immune response. 1- to evaluate the presence of Lewis y and MUC1 in circulating immune complexes (Lewis y/CIC and MUC1/CIC, respectively) and their correlation; 2- to analyze the possible presence of Lewis y in carbohydrate chains of tumoral MUC1 glycoprotein and 3- to correlate serum and tissue parameters considered," investigators in La Plata, Argentina report.
"Pretreatment serum and tissue breast samples from 76 adenocarcinoma, 34 benign and 36 normal specimens were analyzed. Anti-MUC1 and anti-Lewis y MAbs were employed. To detect Lewis y/CIC and MUC1/CIC, ELISA tests were...
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