Hepatocellular Cancer

Research from China Pharmaceutical University has provided new information about hepatocellular cancer

Published in Clinical Oncology Week, February 8th, 2010

"The objective of this study was to investigate the apoptosis-inducing effect of an oxidative analogue of gambogic acid (GA) on the human hepatocellular carcinoma cell line HepG2 and explore the related molecular mechanisms. HepG2 cells were treated with the analogue of GA and the growth inhibition was analysed by MTT assay," investigators in Nanjing, People's Republic of China report.

"The morphological changes in cells were observed under an inverted light microscope and a fluorescence microscope. In addition, both the cell-cycle arrest and the apoptosis rate were detected by flow cytometry. Western blot was used to evaluate the alteration of protein expression. The...

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Source: Clinical Oncology Week (2010-02-08)

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