Protein Arrays

Reports summarize protein arrays study results from Prince of Wales Hospital

Published in Clinical Oncology Week, March 22nd, 2010

According to recent research published in the journal Biochemical Pharmacology, "YC-1 has recently been demonstrated to have potent anti-invasion and anti-metastatic activity in several cancer models, in addition to its anti-proliferation activity. However, the mechanism underlying its anti-invasion/anti-metastatic activity is largely unknown."

"Nasopharyngeal carcinoma (NPC) is a highly metastatic head and neck cancer in Southeast Asia. Here, we demonstrated that YC-1 inhibited invasiveness and proliferation of NPC cells, with the latter being accompanied by PARP cleavage, S-phase arrest and activation of Chk1/Chk2. We aimed at identifying novel anti-invasion...

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Source: Clinical Oncology Week (2010-03-22)

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