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Elsevier

Childhood adversity may promote cellular aging

Published in Clinical Oncology Week, March 29th, 2010

Children who suffer physical or emotional abuse could be faced with accelerated cellular aging as adults, according to new research published by Elsevier in Biological Psychiatry.

It's an easy fact to forget - the aging process begins at birth. Despite this, cellular aging remains somewhat of a mystery, although there is growing evidence that over time, the DNA within cells begins to show signs of aging. One of these signs is the shortening of telomeres, which are DNA "caps" at the end of chromosomes that promote cellular stability.

Telomere length is a measure of biological aging because telomeres shorten progressively with each cell division....

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