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GenVec, Inc.

GenVec Discontinues Phase 3 Clinical Trial of TNFerade

Published in Clinical Oncology Week, April 12th, 2010

GenVec, Inc. (NASDAQ:GNVC) announced that it is discontinuing its Phase 3 clinical trial of TNFerade™ in patients with locally advanced pancreatic cancer based on results of an interim analysis. This interim analysis of overall survival, conducted after the 184th death (two-thirds of total expected events), was designed to determine whether the study should continue.

GenVec has determined, after conferring with its independent Data Safety Monitoring Board, that the PACT trial would not meet the goal of demonstrating persuasive evidence of clinical effectiveness that could form the basis for regulatory approval in the population chosen for study. This randomized,...

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