Glioblastoma

Studies from Tokushima Bunri University, Faculty of Pharmaceutical Sciences have provided new data on glioblastoma

Published in Clinical Oncology Week, June 14th, 2010

Data detailed in 'Effects of kaempferol on the mechanisms of drug resistance in the human glioblastoma cell line T98G' have been presented. "Food contains components that may either increase or decrease the bioavailability of a drug. In particular, it is known that grapefruit juice and St," scientists writing in the journal Pharmazie report.

"John's Wort induce drug interactions via an effect on the drug-metabolizing enzyme cytochrome P450 (CYP). However, interactions with membrane transporters, such as P-glycoprotein and multidrug resistance-related protein (MRP), may also influence drug bioavailability. The objective of the present study was to investigate the...

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Source: Clinical Oncology Week (2010-06-14)

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