Squamous Cell Carcinoma
Findings from University of Brasilia Provide New Insights into Squamous Cell Carcinoma
Published in Clinical Oncology Week, February 14th, 2011
2011 FEB 14 -- "To the workup of metastatic squamous cell carcinoma (SCC) of unknown primary, we studied an immunohistochemical panel including thyroid transcription factor (TTF-1), napsin A, villin, CDX-2, K903, CK5/6, p63, p16, CK7, and CK20. Using tissue microarray, we compared 194 SCC cases from the following sites: 35 lung, 34 skin, 14 cervix, 4 vagina, 16 vulva, 8 penis, 9 anus, 3 rectum, 10 esophagus, 4 bladder/urethra, and 57 SCC from various head and neck sites. p63 and K903 stained positively in 100% of cases, and CK5/6 in nearly 100% of cases, with the exception of 1 lung," investigators in Brasilia, Brazil report.
"CK7 was positive in 31.6% of...
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