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Gliomas

Findings from M.D. Anderson Cancer Center Advance Knowledge in Gliomas

Published in Clinical Oncology Week, December 26th, 2011

2011 DEC 26 -- Data detailed in "The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells" have been presented. According to the authors of recent research published in the journal Neuro-oncology, "BBR3610 is a polynuclear platinum compound, in which two platinums are linked by a spermine-like linker, and studies in a variety of cancers, including glioma, have shown that it is more potent than conventional platinums and works by different means. Identifying the mechanism of action of BBR3610 would help in developing the drug further for clinical use."

"Previous work showed that BBR3610 does not...

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