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Giant Cell Tumors

New Giant Cell Tumors Study Findings Have Been Reported by Researchers at Brigham & Women's Hospital

Published in Clinical Oncology Week, January 16th, 2012

2012 JAN 16 -- Investigators discuss in "p63 immunohistochemical staining is limited in soft tissue tumors" new findings in Giant Cell Tumors. "p63 is a p53 homolog that is expressed in various normal epithelial tissues and epithelial malignancies. Its expression in mesenchymal lesions has not been examined in depth; therefore, we studied p63 expression by immunohistochemical analysis in 650 soft tissue tumors," scientists in Boston, Massachusetts report.

"We found that p63 expression is limited in soft tissue tumors. The majority of tumors studied were p63-, including all cases of angiosarcoma, lipomatous neoplasms, dermatofibrosarcoma protuberans,...

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