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Clinical Trials Week

Susan Hasty, Publisher

Table of Contents . . . October 6th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Clinical Trials Week | Other Publications

Breast Cancer - Can healthy bones help prevent metastasis?

Head and Neck Cancer - Faster radiotherapy more effective

Alcoholism - Chronic drinking increases cortisol during intoxication and withdrawal

Breast Cancer - Researchers develop model for early detection of breast cancer

Hip Replacement - 80% of patients eligible for minimally invasive surgery

Parkinson Disease - New clinical research study evaluates novel cell therapy

AIDS Therapy - Study: Patients can benefit from simplified antiretroviral treatments

Adverse Drug Effect - Vaginal natamycin treatment during pregnancy does not harm the fetus

Angina - Heart patients may benefit from VEGF gene transfer

Angiology - Fibrinolytic factors are not useful in predicting risk of thromboembolism

Anticancer Drugs - Marine-derived anticancer agents are evaluated in clinical trials

Aspergillosis - Better outcomes and cost savings for life-threatening fungal infections

Breast Cancer - Docetaxel and capecitabine improve survival in metastatic breast cancer

Breast Cancer - Phase II clinical trial of MDX-010 launched

Breast Cancer - Study tests examestane for use after 5 years of preventive tamoxifen

Cancer Immunotherapy - GeneMax Corp. announces agreement for the production of TAP cancer vaccine

Cancer Metastasis - Zoledronic acid is effective in managing metastatic bone disease

Cancer Therapy - Javlor (Vinflunine) enters in phase III clinical trials

Cardiac Arrhythmia - FDA grants approval to start atrial fibrillation study

Cardiac Arrhythmia - Patient enrollment completed in cryoblation study

Caregiver Health - Learning skills greatly limits stress for family caregivers, study finds

Colorectal Cancer - A medical nutriment has supportive value in the treatment of colorectal cancer

Diarrhea - Trial shows Probactrix is effective for treating diarrhea caused by antibiotics

Drug Delivery - AERx pain management system study data published

Endocrinology - Triphasic oral contraceptive decreases bone turnover in premenopausal women

Finance - Med-eMonitor developer completes bridge financing

Geriatrics - Alzheimer drug trials should include a brain biopsy for beta-amyloid level

Heart Disease - Acetaminophen may be best for patients on cardioprotective aspirin therapy

Hemophilia B - Clinical trials of Coagulin-B to resume

Hyperparathyroidism - New drug application submitted for cinacalcet HCl

Immunology - Two phase II clinical trials for Vitaxin begin

Information Technology - Alliance to bring added automation to Oracle clinical users

Legal Issues - Patent issued covering cremophor-free taxanes

Lung Cancer - Combined CPT-11 and ifosfamide is effective in relapsed SCLC

Market Analysis - Driving market uptake through successful physician messaging

Melanoma - Phase II study demonstrates vaccine effectiveness in half of patients

Melanoma - Positive results reported in phase III trial of Genasense plus chemotherapy

Melanoma - Two clinical milestones achieved for Vitaxin

Ovarian Cancer - New phase of Northern Ireland screening trial launched

Ovarian Cancer - Paclitaxel temporarily adds to the sensory neurotoxicity of cisplatin

Ovarian Cancer - Royalty rights to R1549 obtained by U.K. biotech company

Pain Relief - NWT 4000 preparing for clinical trials, expects to seek FDA approval

Pain Therapy - Positive phase III results for bicifadine, a novel, non-narcotic analgesic, announced

Pancreatic and Prostate Cancer - Financing secured for the development of cancer vaccines

Parkinson Disease - Company to assist Neurologix in management of gene therapy trial

Parkinson Disease - FDA response provided on special protocol assessment for Altropane

Personnel - Gennevois named VP of medical affairs at cardiovascular device company

Personnel - Zelefsky named to board of directors at pharmaceutical firm

Pharmaceutical Approvals - European Union approves Humira; FDA approves Depakote ER

Pompe Disease - Myozyme development program expanded

Prostate Cancer - Promising results reported on new protease activated therapy

Psoriasis - Clinical trials for Psoraxine initiated

Psoriasis - Design of trials in psoriasis provides lessons for clinical practice

Restenosis - Angioplasty device company starts clinical studies of catheter

Schizophrenia - FDA approves ABILIFY (Aripiprazole) sNDA

Staphylococcus - Company successfully completes StaphVAX immunogenicity study

Staphylococcus - Phase I study of Aurexis finished

Telemedicine - Home care trial planned for heart failure patients

Vitamin C - Vitamin C supplementation reduces constitutive ICAM-1 expression

West Nile Virus - Clinical trial of West Nile virus patients begins

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