Clinical Trials Week

Heart Disease - Cilostazol reduces coronary artery stent restenosis by 40%

Heart Pumps - Site selection nears completion for trial of DeBakey VAD for destination therapy

Hematology - Single agent thalidomide won't help those with relapsed acute myeloid leukemia

Hepatitis C VIrus - Safety trial initiated for experimental hepatitis C drug treatment

Inflammation - Pathway found implicating superoxide as important mediator of inflammatory pain

Insomnia - FDA extends PDUFA action date for Estorra NDA

Insulin Research - Company to reacquire rights and data from alliance on modified insulin products

Japanese Encephalitis - Chimeric attenuated vaccine protects against Japanese encephalitis

Kidney Disease - Research program to study effects of D-Receptor activation

Leukemia - Positive Dacogen data presented at chemotherapy conference

Leukemia Therapy - In AML patients, pretransplant MRD status predicts auto-SCT outcome

Limb Ischemia - Data reported from gene therapy using engineered form of the HIF-1alpha

Lung Cancer - Weekly carboplatin and paclitaxel in elderly non-small cell lung cancer patients

Macular Degeneration - New anecortave acetate clinical trials initiated

Market Analysis - Clinical trial communication plans can be helped with toolkit

Melanoma - Genasense may improve activity of anticancer therapy

Myocardial Infarction - Study: Newer formulation of heparin improves outcomes

Non-Hodgkin Lymphoma - Phase III trial of Rituxan maintenance reaches efficacy endpoint early

Obesity Therapy - Oxyntomodulin suppresses appetite and reduces food intake in humans

Otitis Media - 7-Valent pneumococcal conjugate vaccine effective against otitis media

Ovarian Cancer - A phase II trial of bryostatin-I in recurrent epithelial ovarian carcinoma

Pain Therapy - Approval granted for phase II trial of AeroLEF

Patents - Patent office allows additional patent claims to STR for cancer therapy

Postoperative Ileus - Enrollment completed in phase III study 308 of Entereg

Premature Birth - U.S. study initiated in pregnant women at high risk of preterm delivery

Prostate Cancer - Improving quality of life in men with prostate cancer

Prostate Cancer - Phase III trial of Acapodene initiated for the treatment of androgen deprivation

Prostate Cancer - Pivotal Eligard 45-mg phase III clinical study

Prostate Cancer - Provenge phase III data shows extended survival time

Pulmonary Arterial Hypertension - Pulmonary arterial hypertension treatment data shows prolonged survival

Renal Disease - At-home dialysis an effective option for more patients

Rheumatoid Arthritis - Phase IIb clinical trials of Pralnacasan discontinued due to toxicity

Rheumatoid Arthritis - Positive data reported on rheumatoid arthritis treatment study

Thoracic Aneurysms - Talent Thoracic Stent Graft study begins

Translational Research - New strategy aims to make U.K. bioscience sector a world beater

Uveitis - Drug delivery technology for ophthalmology applications presented

Vertebral Compression Fractures - FDA grants investigational device exemption for bone void filler clinical study

Wound Healing - Study results indicate Oasis may be "more likely to heal"