Clinical Trials Week
Susan Hasty, Publisher
Table of Contents . . . December 29th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Clinical Trials Week | Other Publications
Leukemia - First patient enters pivotal phase II study for clofarabine
Pediatrics - Practice-based intervention improves quality of care for young children
Adverse Drug Effects - Antiemetic improves control of chemotherapy-induced nausea, vomiting
Drug Development - Safety and efficacy of tipranavir reviewed
Rheumatoid Arthritis - AVR118 inhibits inflammatory arthritis
Acne Therapy - Madison Keats to assist in identifying a licensing partner for PCL-016
Acute Lymphocytic Leukemia - Gleevec shows promise in treating another form of leukemia
Alzheimer Disease - Canada approves start of human safety testing for GT 1061
Alzheimer Disease - LSU Health Sciences Center initiates clinical trial of COGNIShunt System
Anthrax - Antibodies may provide option to vaccines, antibiotics
Anticancer Drug Clearance - Tumor-up-regulated cytochrome P4501B1 enzyme can be targeted by cytotoxic T cells
Atopic Dermatitis - First phase II clinical trial of dermatology drug, NPI 32101, begins
Bipolar Mania - FDA approves Risperdal as monotherapy or in combination with lithium, valproate
Breast Cancer - Advexin vaccine therapy to begin phase I/II
Breast Cancer - Docetaxel-based regimen improves survival and disease-free survival, data show
Breast Cancer - NDA completed for treatment of breast cancer with brain metastases
Breast Cancer - New studies launched with Modrenal
Breast Cancer - Novel molecular transporter mechanism reported on albumin-bound paclitaxel
Breast Cancer - Positive survival, quality of life data presented on RSR13 phase III study
Cancer Therapy - ILEX, collaborator, complete development of an oral clofarabine formulation
Cardiovascular Disease - Genomics-derived (Lp-PLA2) inhibitor to advance to phase III trials
Cardiovascular Disease Therapy - Lipid therapy effective in clinical setting
Chemotherapy - High-dose granisetron is safe and well tolerated
Collaborations - Nitric oxide-enhancing compound advances; NitroMed gets second payment
Colorectal Cancer - Company enrolling for phase II clinical trial of Litx for liver metastases
Embolic Stroke - Permanent carotid diverter product is implanted for the first time in a human
HIV/AIDS Pediatric - Genetic factors influencing pediatric HIV progression and neurotoxicity identified
Hepatitis C Virus - Positive interim results of phase IB trial of isatoribine reported
High Cholesterol - Positive results reported on phase I study of ETC-1001
Imaging Agents - Phase III clinical trial involving binodenoson commences
Leukemia - AP23464 is effective in Gleevec-resistant leukemia cells
Lung Cancer - Biotech company in-licenses phase I anticancer drug from Sankyo
Neurodegenerative Disorders - Phase I trial of EHT 0202 initiated
Prostate Cancer - Male lumpectomy is a promising new treatment
Schizophrenia - Risperdal Consta launched as first new schizophrenia treatment in 14 years
Short Bowel Syndrome - FDA approves Zorbtive for rare gastrointestinal condition
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