Susan Hasty, Publisher
Table of Contents . . . April 5th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Clinical Trials Week | Other Publications
HIV/AIDS Therapy - Routine resistance testing can improve ART outcome in experienced patients
Transplant Medicine - Effect of CyA on big ET-1 levels 1 year after OHTx characterized
Breast Cancer - Oncologist calls for new guidelines on early reporting from clinical trials
Breast Cancer - Study demonstrates clear survival benefit of treatment in clinical trials
Cancer Therapy - Renal cancer human trial of phenoxodiol in combination therapy begins
Acute Coronary Syndrome - New study demonstrates the benefits of intensive statin therapy
Anthrax - ABthrax found to be safe and well tolerated
Benign Prostatic Hyperplasia - Milestone payments received, first patients treated with Prolieve
Brain Cancer - Hudson licenses radiosensitizer IPdR
Breast Cancer - Breast cancer patients switched to Aromasin more likely to remain cancer free
Breast Cancer - Caelyx demonstrates efficacy, reduced cardiac toxicity
Breast Cancer - Epirubicin, vinorelbine, and cisplatin are effective in advanced breast cancer
Breast Cancer - First large-scale trial of genetically personalized treatment to start soon
Breast Cancer - NDA filed with FDA for nanoparticle-based Abraxane
Breast Cancer - Preoperative treatment with anastrozole reduces need for extensive surgery
Breast Cancer - Results of comparison study favor exemestane for advanced disease
Breast Cancer - Study: Patients switched to AROMASIN more likely to remain cancer-free
Business & Finance - ESTRASORB maker announces revenue increase for quarter, decrease for 2003
Business & Finance - FluMist maker announces plan to achieve $2 billion in revenues by 2009
Cancer Therapy - Genetronics engages CRO for U.S. and European clinical trials
Cardiovascular Disease - Cardiac MRI a better predictor of heart attack, death for women
Cardiovascular Disease Therapy - Beta-blocker treatment feasible for many asthma, COPD patients
Cardiovascular Disease Therapy - Cardiac resynchronization reduces all-cause mortality risk
Chemotherapy-Induced Nausea - Aloxi injection incorporated into NCCN antiemetic guidelines
Chronic Hepatitis C - The ribavirin prodrug viramidine has proven safe in healthy volunteers
Chronic Obstructive Pulmonary Disease - COPD outcomes study completes patient recruitment
Chronic Pain Management - Company launches phase I clinical trials for chronic pain drug
Colon Cancer - Phase II colorectal vaccine trial results updated
Coronary Artery Blockage - Data supports performance of CYPHER Sirolimus-eluting Coronary Stent
Diagnostics - Positive PYY obesity and apomorphine sexual dysfunction trial data reported
Diarrhea - Trial results advance development of vaccine for travelers' diarrhea
Ear Infections - FDA approves once-daily Floxin Otic (ofloxacin otic solution)
Finance - Autoimmune disease drug maker completes raises $57 million
Finance - Trial-monitoring company announces final closing of private financing
Finance - Vaccine development helps drive company's 25% revenue increase in 2003
Finance - Women's health pharmaceutical firm reports loss of $0.20 per share
Glaucoma - Clinical data on Travatan/Timolol Fixed Combination reported at glaucoma meeting
Heart Failure - Implantable defibrillators reduce death by 23% in trial
Heart Failure - Study raises questions about chronic diuretics and renal insufficiency
Herpesvirus - Common virus may contribute to uncommon bone disease in children
Hypertension Therapy - Bosentan represents improved approach for pulmonary arterial hypertension treatment
Immunology - Data presented on molecular mechanism of action for HE2000
Immunology - Positive results reported from Xibrom U.S. phase III trials
Informed Consent - Medical privacy law makes health research harder, more expensive
Insomnia - Company sees positive results for indiplon in adults with transient insomnia
Licensing Agreement - Geron Corp. inks agreement for therapeutic cancer-vaccine technology
Liver Cancer - First patient accepted in phase III liver cancer study
Melanoma - Board recommends continuations of Canvaxin phase III trial
Myocardial Infarction - Pexelizumab mortality benefit reported from multiple trials
Myocardial Infarction - Study demonstrates efficacy of automated external defibrillator
Overactive Bladder - Phase I trial for Oxybutynin gel completed
Pain Therapy - First patients dosed in phase II AeroLEF trial for post-surgical pain
Solid Tumors - 2-Deoxy-D-Glucose phase I trial initiated for solid tumor treatment
Squamous Cell Carcinoma - Docetaxel, cisplatin and 5-FU are effective in squamous cell carcinoma
Staph Infections - Company initiates enrollment in phase II trial for Aurexis
Stroke - Stent trials demonstrate positive outcomes in high-risk patients
Systemic Lupus Erythematosus - LymphoStat-B selected for FDA's Pilot 2 Program
Tumor Suppression - ARRY-142886 cleared to advance into human clinical trials
Vaccine Efficacy - Vaccination for neurotropic disease recommended in children with brain tumors
Wound Care - Study demonstrates HealthRenu effectiveness in infection prevention
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